My Queen Fitted Sheet is now a rather permanent fixture on my bed. Underneath this layer are the mattress protector and a set of cotton sheets. And I sleep on a Queen Flat Sheet that I place over this fitted sheet.
What this means is a very clean bed and very much less laundry to do. Lots of water and detergent savings. No smells from sweat or from unintentional spills and thrills. And if a wipe down is required, just wipe it off with a mild detergent. Completely fuss free.